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All participants had a diagnosis of ASD established with DSM-IV-TR or DSM-5 and validated with ADOS-2 and/or ADI-R, while individuals with neurological or psychiatric comorbidities, recent probiotic or oxytocin use, or unstable medications were excluded

Systemic Effectiveness : Interestingly, BPC 157 can be injected systemically (e.g., in the abdomen) rather than directly at the injury site, and still provide benefits throughout the body

Here, elevated NO production as a result of increased activation of NOXs, in particular NOX4 leads to the stabilisation of HIF-1 and thus promotion of endothelial cell (EC) survival, migration, differentiation, and therefore neovascularisation 64,106,107,108

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This approach recognizes that laparoscopy may not change initial management and allows earlier initiation of appropriate therapy